6 Weeks into TRT. Optimization Advice?

I let my little brother believe in Santa Claus for several years after I found out the truth. Carry on.

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@dextermorgan LMAO I love you man.

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This is what I was thinking… I have no idea why OP would consider going on TRT with those numbers… I would have been looking for something else…

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I’ll say it’s about wellness… What I’ve been been experiencing the last several years is not me. I’ve always been calm, happy, clear headed and able to take on anything without hesitation. I feel like I’m back to that state mostly.

I have done a lot of reading here over the last week and want to make a change to my schedule and method.

Old method. 100mg T Cyp IM every 3.5 days. Arimidex was used inconsistently

New method. 60mg T Cyp SubQ MWF. Arimidex .5mg with each injection.

Thoughts?

You’re obsessing over numbers and made zero indication as to how you actually feel or if you have any symptoms. This matters more than the numbers which everyone else is obsessing over instead of asking the most important question.

If you had an understanding as to the role of estrogen in men, you’d realize your AI dose is insane. Ditch it.

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Nope, skip this part

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I did indicate how I feel earlier. I will elaborate. I feel like my libido and sex drive could be better. My ability to maintain an erection has been off and on the last 4 weeks. At times it is fine at other times Iose it. I don’t know if this is caused by an E level of 130. When I first started TRT I woke up with an erection frequently. That lasted 3 weeks. I Generally feel very good. My theory based on my reading is that lowering my dose to 180, injecting subQ will lower my estrogen conversion. That’s the thought. Am I off base? I don’t have enough experience to know for sure though.

You should not be on a twice weekly protocol because you’re aromatising way too much and need daily injections to minimize the aromatization. That AI dosage is just too high, you should start at .125 anastrozole. It would be best if you dropped it altogether and just increase/decrease your daily dose to dial in.

You might even have better luck on T cream applied to the scrotum which tends to convert to testosterone and DHT more than it does to estrogen, in fact in a lot of cases estrogen is significantly lower and no longer a problem.

This isn’t universal, I aromitasized like crazy on SQ injections. It was the worst experience of my life.

I give up.

Everybody take @systemlord’s advice and start taking an AI today. 3mg a week. That should do it. Symptoms or not. You all have estrogen dominance. Your T levels are irrelevant. If you aren’t having nightmares about estrogen yet it’s because you’re not taking enough AI.

Forget what all the doctors say on my YouTube channel. They’re all wrong. Forget all the posted literature we’ve provided on the subject. They’re also all wrong. Totally made up. Works of fiction. Only systemlord is right.

All kneel to systemlord.

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Hmm. My thought is that I don’t want to change too many things at one time. Cream may be better. Idk. I was looking to try this for 6 weeks and take a blood test.

@dbossa. Chill. I’d like your opinion based on my post.

Find my email in my bio and I’ll give you a hand.

Do not follow a damn thing systemlord says as I can demonstrate it to be false a hundred different ways. It is advice like that which floods these forums with guys having issues.

Email sent.

I just wanted you to put that on the back burner.

Hi Everyone,

I wanted to provide an update to my TRT journey. I made my original post after week 6. I received a lot of good advice and decided to make a few changes based on input here.

First Blood Test Week 0 - Before TRT.
TESTOSTERONE, TOTAL, MS 645 NORMAL 250-1100 ng/dL 03
TESTOSTERONE, FREE 97.8 NORMAL 35.0-155.0 pg/mL 03
ESTRADIOL,ULTRASENSITIVE, LC/MS 54 HIGH < OR = 29 pg/mL 02
DHEA SULFATE 360 NORMAL 70-495 mcg/dL 01
TSH 2.66 NORMAL 0.40-4.50 mIU/L 01
PSA, TOTAL 3.8 NORMAL < OR = 4.0 ng/mL 01
RED BLOOD CELL COUNT 6.02 HIGH 4.20-5.80 Million/uL 01
HEMOGLOBIN 18.8 HIGH 13.2-17.1 g/dL 01
HEMATOCRIT 52.5 HIGH 38.5-50.0 % 01
CHOLESTEROL, TOTAL 253 HIGH <200 mg/dL 01
HDL CHOLESTEROL 71 NORMAL >40 mg/dL 01
TRIGLYCERIDES 108 NORMAL <150 mg/dL 01
LDL-CHOLESTEROL 160 HIGH mg/dL (calc) 01

Second Blood Test Week 6
TESTOSTERONE, TOTAL, MS 1478 HIGH 250-1100 ng/dL 03
TESTOSTERONE, FREE 301.9 HIGH 35.0-155.0 pg/mL 03
ESTRADIOL,ULTRASENSITIVE, LC/MS 130 HIGH < OR = 29 pg/mL 02
DHEA SULFATE 417 NORMAL 70-495 mcg/dL 01
TSH 1.83 NORMAL 0.40-4.50 mIU/L 01
PSA, TOTAL 3.1 NORMAL < OR = 4.0 ng/mL 01
RED BLOOD CELL COUNT 5.50 NORMAL 4.20-5.80 Million/uL 01
HEMOGLOBIN 17.5 HIGH 13.2-17.1 g/dL 01
HEMATOCRIT 50.0 NORMAL 38.5-50.0 % 01
CHOLESTEROL, TOTAL 226 HIGH <200 mg/dL 01
HDL CHOLESTEROL 58 NORMAL >40 mg/dL 01
TRIGLYCERIDES 97 NORMAL <150 mg/dL 01
LDL-CHOLESTEROL 147 HIGH mg/dL (calc) 01

Third Blood Test Week 14
TESTOSTERONE, TOTAL, MS 1662 HIGH 250-1100 ng/dL
TESTOSTERONE, FREE 516.7 HIGH 35.0-155.0 pg/mL
ESTRADIOL,ULTRASENSITIVE, LC/MS 192 HIGH < OR = 29 pg/mL
DHEA SULFATE 327 NORMAL 70-495 mcg/dL
TSH 3.00 NORMAL 0.40-4.50 mIU/L
PSA, TOTAL 3.2 NORMAL < OR = 4.0 ng/mL
RED BLOOD CELL COUNT 5.81 HIGH 4.20-5.80 Million/uL
HEMOGLOBIN 17.7 HIGH 13.2-17.1 g/dL
HEMATOCRIT 51.3 HIGH 38.5-50.0 %
CHOLESTEROL, TOTAL 233 HIGH <200 mg/dL
HDL CHOLESTEROL 54 NORMAL > OR = 40 mg/dL
TRIGLYCERIDES 70 NORMAL <150 mg/dL
LDL-CHOLESTEROL 162 HIGH mg/dL (calc)

Fourth Blood Test Week 24
TESTOSTERONE, TOTAL, MS 1264 HIGH 250-1100 ng/dL
TESTOSTERONE, FREE 370.7 HIGH 35.0-155.0 pg/mL
ESTRADIOL,ULTRASENSITIVE, LC/MS 32 HIGH < OR = 29 pg/mL
DHEA SULFATE 294 NORMAL 38-313 mcg/dL
TSH 3.63 NORMAL 0.40-4.50 mIU/L
PSA, TOTAL 3.5 NORMAL < OR = 4.0 ng/mL
RED BLOOD CELL COUNT 6.25 HIGH 4.20-5.80 Million/uL
HEMOGLOBIN 18.7 HIGH 13.2-17.1 g/dL
HEMATOCRIT 53.2 HIGH 38.5-50.0 %
CHOLESTEROL, TOTAL 248 HIGH <200 mg/dL
HDL CHOLESTEROL 50 NORMAL > OR = 40 mg/dL
TRIGLYCERIDES 133 NORMAL <150 mg/dL
LDL-CHOLESTEROL 171 HIGH mg/dL (calc)

From week 8 to 14 my protocol was 200mg T-Cyp per week split up and injected M/W/F. I started out with AI but decided to drop it. The results of this protocol are shown in my blood test from week 14.

From week 15 to 24 my protocol was 154mg T-Cyp per week split up into ā€œdailyā€ injections. I also took exactly .15mg Arimidex every day at the same time as my T-Cyp injection.

I definitely feel like my E2 level at 192 was very high from week 8 to 14. I had a lot of water retention and emotional spikes. I will say that libido was high though.

From week 15 to 24 I definitely feel like daily injections smoothed out my hormone levels. At times I felt a little flat emotionally and was worried my E2 had crashed. Overall the effect of daily injections I feel is good.

Next steps: I am going to go down to 140mg T-Cyp a week injected daily and lower my Arimidex daily dosage to .1mg or .07mg per day.

Let me know any thoughts you all have. I appreciated your feed back in the first round of posts!

Edit: Adding. I have been giving blood after every blood test.

Only the body should be left to regulate the estradiol. People massively dont understand estradiol is a paracrine hormone and it should just be left as it is.

I can accept only a bit if a debate here when hcg comes into play because it inflates estradiol too much by not so natural mechanism of production(the mechanism is natural but not the rate and amount it is produced)

So what would you do vonko? Are you saying just don’t use any Ai? The only thing I haven’t done is do daily injections with no Ai. I’ve got a thought that I may try to slowly taper the Arimidex just to see how I would feel.

I say you need to completely ditch AI for good it is not needed on TRT, the latest research shows it is not needed in supra-physiological doses as well.

Estradiol is as important as testosterone for the success of a TRT regimen and I would say your e2 value of around 30 is quite low for the t levels you maintain. When you raise your t your e2 must raise accordingly. If your t is above the lab ranges it is very natural e2 to be above as well.

Your body knows best how to balance estradiol, there are very few cases of people who dont aromatize enough Ive seen such. The only case where this balance may be broken in terms e2 to get too much is when using HCG but I dont think that is the case.

Injection frequency is something completely separate from e2. It should be according to your shbg. If you feel hormonally unstable yes increase frequency.

And remember give every change of protocol at least 6 weeks to work, no matter whether it is dropping AI or changing frequency. I recently changed my t ester and for 4 weeks I felt like shit until I started to feel better.

One more thing about arimedex - remember it is a drug developed for women with breast cancer. A kind of chemotherapy. Such drugs are developed for lifesaving situations with much disregard of their side effects and are not intended for long term use. Do you wanna put this in your body for the rest of your life?

On your place I would forget about any e2 concerns, but I would focus on the erythocitosis.
Why are you climbing tour blood counts so quickly when you are donating blood? You gotta find the underlying issue here.

Are you a smoker, have you tested for sleep apnea and what is your body fat percentage? How much water do you drink per day? Much more important questions than your e2 bro :slight_smile: