38 YO Starting TRT

So what can be done to raise E2 levels? As high as my free-T is, I would expect it to be higher anyways. Don’t understand why it’s that low.

My iron levels now are fine. I was referring to about a year ago. My blood counts were low with low ferritin as well. Sorry, should have clarified that better.

I’ll ask the doc about rt3 when I see him.

Why don’t I see prolactin levels. This would make sence before an MRI …

From what I see estradiol is raising on its own…

Adding hcg would raise it.

Meca root is suppose to balance hormones.

If u change anything you need to monitor e2 regularly to make sure it doesn’t get to high hcg or clomid would increase intertesticular testosterone but if u get it to high you may feel worse then you do now.

When you say you don’t feel well could you please explain this?

What are all your symptoms even the minor ones

Dang, I keep leaving stuff out. Think this is the last.

PROLACTIN 3.6 (2.0-18.0 ng/mL EN)
PSA, TOTAL 0.7 (< OR = 4.0 ng/mL)
DHEA SULFATE 378 H (110-370 mcg/dL)

If u think you need a MRI for a pituitary tumour I see no evidence of any overly secreted hormones from there… If I was your insurance company I’d say no :slight_smile:

I don’t know if I do or not, the pituitary specialist group I’m waiting to see thinks I should. No, none of my hormones are being overproduced that I know of. But a lot are being suppressed. Which from what I’ve read can be caused by a tumor as well. Either way I’m convinced there is a problem with the pituitary/hypothalamus. I’ve had no head trauma, so not sure what would have caused it to suddenly stop working.

Fsh is not deprived… Lh is low but has a short half life.

What time of day did you take the labs…

Do you get a good night sleep?

Do you feel refreshed from your sleep when you wake up?

Do you snore?

I asked you to tell us what your symptoms are when you say you don’t feel we’ll?

Are you eating good?

Our foods are full of shit these days no wonder everyone is sick.

Please list symptoms even the ones u don’t think matter.

When I say suppressed, I don’t mean gone, just lower than it should be. These last labs were taken first thing in the morning (fasting). I don’t usually snore. Don’t usually feel refreshed in the mornings either.

Symptoms:
Drink a lot / pee a lot. - According to the docs, related to the pituitary, likely not enough ADH being made. Drink multiple liters of water a day. And since the kidneys apparently aren’t getting the signal to conserve water, it pretty much goes right through me. Been going on quite a bit before anything else.

Tinnitus in both ears - saw an ENT who said there was really nothing he could do. This started a couple months before the rest of the low-t symptoms. Hasn’t stopped for even a minute.

Pre-diabetes - keeping it in control with low carb diet. First sign was reactive hypos which my doc thought were panic attacks. He prescribed an SSRI which I took 2 doses of and had an adverse reaction. It was only a few days after that the low-t symptoms started.

When I’m feeling bad, it’s basically physical and mental fatigue. Can’t think straight/brain fog, don’t have energy or ambition to do anything, etc. Even though the TRT has helped improve that, I can say I still have not had a day where I felt as good as I used to when all this started over a year ago.

My diet is basically low carb to keep my blood sugar in check . I stay away from processed as much as possible. Only water to drink for close to a year now.

Frequent thirst and urination is also assign of diabetes and adrenal fatigue… The tinnitus has me concerned… Have you ever been bitten by a tick?

I have the same problems a you my friend and I am being tested for Lyme desiese this week. Not something you want to ignor or fuck around with.

I’m suspecting rt3 problems.

If your interested in getting tested for Lyme find a way to order the labs from Igenex in California.
Not saying you have it but it is becoming an epidemic these days.

I will point out that if not treated it will get worse and will mess with your endocrinal systems… Do you have any muscle or joint pain? Do you have hot flashes?

Forgot the other symptom - head pressure (not painful), just pressure. Been going on so long I just don’t even think about it.
Don’t believe the thirst is blood sugar related, I keep it well-controlled.
No joint/muscle pain or hot flashes.

I am curious what’s keeping my E2 so low. Especially since my free-T is above range.

Just got these results sent to me. Lab was drawn on 6-20-2013.

TESTOSTERONE, FREE,BIO SLI
AND TOTAL, LC/MS/MS
TESTOSTERONE, TOTAL, 585 (250-1100 ng/dL)
TESTOSTERONE, FREE 113.8 (46.0-224.0 pg/mL)
TESTOSTERONE,BIOAVAILABLE 258.8 (110.0-575.0 ng/dL)
SEX HORMONE BINDING GLOBULIN 20 (10-50 nmol/L)
ALBUMIN,SERUM 5.0 (3.6-5.1 g/dL)

I had just started splitting my dose to 40mg twice a week. Labs were taken about 48 hours after last injection.

E2=7: This is odd. Not obvious what to do about this. Higher dose hCG could be attempted.

[quote]KSman wrote:
E2=7: This is odd. Not obvious what to do about this. Higher dose hCG could be attempted.[/quote]

I know, all labs I’ve had done have shown low E2. I have’t taken HCG before. Unfortunately won’t be seeing the hormone specialist until August 1.

Your labs went from a 6 to a 13 it says even in the stickies E follows T. No reason not to assume it will raise a bit more. I do not think that ft3 being out of range is something to ignore and your endo was shrugging it off.w

I had almost identical labs and I have a enlarged thyroid. Discription on ksman is here… You have to take control of your health. Most docs are idiots. As ks says

The high FT3 was from a year ago. The most recent labs I posted appears to be fine.

Hey all, been a while. I’ve been taking 60mg T 2x a week since Aug and these are the lastes labs I just got back. Obviously my T levels are fine but still not feeling great. These labs show elevated RT3, low ferritin, and high free testosterone. Labs were taken a couple of hours before my next injection.I’ll be seeing the doc again on Monday. Last I saw him he seemed to think I could be experiencing adrenal fatigue and gave me supplements to try and help.

fT3 should be near mid range, 3.4
So I see hypothyroidism
What are temperatures and iodine intake as per thyroid basics sticky?

With low fT3 and rT3 blocking what fT3 you have, this is a bad combination.

But what can increase fT3? Stress, chronic infection [stress]

When I see elevated WBC and CRP, I see chronic low grade infection and inflammation

What can that be? For you T levels, your HTC and RBC seem lowish.

And your ferritin is LOW.

My working conclusion is that you have a condition with a GI bleed.

  • get an occult blood test kit from doc, you smear poop on it and mail it, doc gets results
  • get liver and kidney lab panel, start with ALT/AST
    – do not do with sore muscles, lay off strenuous exercise for 3-4 days

Get Wilson’s book on ‘adrenal fatigue’ from amazon.com

Work through implications of thyroid basics. You have two major issues that I can see.

Sorry, cannot candy coat this. Ping me again when you have body temps and iodine posted.

Show this to your doc. If he is not interested, get a new doc.

[quote]
When I see elevated WBC and CRP, I see chronic low grade infection and inflammation[/quote]

Im guessing the WBC is because I had just gotten over a cold when the labs were taken. The CRP is actually WAY down from last labs. I’m hoping they’re still on their way down. next labs will tell.

I had just given blood a few weeks before the labs. My last labs showed high HCT.

[quote]And your ferritin is LOW.

My working conclusion is that you have a condition with a GI bleed.

  • get an occult blood test kit from doc, you smear poop on it and mail it, doc gets results
  • get liver and kidney lab panel, start with ALT/AST
    – do not do with sore muscles, lay off strenuous exercise for 3-4 days[/quote]

I had the fecal occult test last time my feritin was low and it came back fine. Assumed it was due to frequent blood donations. Don’t think that would be the case this time. I’ve only donated once. I’ve also had plenty other kidney/liver panels over the past year and they always came back fine. I feel either I have an iron absorption issue or something else that hasn’t been tested for yet.

Overall I agree with you that the thyroid numbers aren’t right, I’m sure my doc will agree. Just have to wait for Monday and see what he has to say about the next steps.

I just got back from my Doc and I took in your lab results and my comments. He agreed with the GI bleed concern. He was not too concerned with the WBC but did think that CRP was a concern. CRP and rT3 can be related.

Looking back at this thread. With the amount of water going through your system, you are probably deficient in water soluble vitamins, perhaps some electrolytes.