I was hoping so, just wasn’t sure how much those on it, had thyroid issues to go along with it. Everyone I have seen post post about metformin have just been for the other benefits it seems.
It’s one of the most studied drugs in the world. Have you tried pubmed?
No I was only googling to see what tests and articles would pop up. I will look into pubmed.
Any studies you find behind pay walls copy the article and go to sci-hub.tw and you’ll be able to view them
My thyroid number couldn’t be better so I have no data if metformin helps there. I have been on metformin for just about a year now and I have 4 blood test and hundreds of finger stick reading so I plan to go off when my bottle runs out. I want to see if anything changes. As for body composition or any kind of feeling better I have noticed nothing. My A1C before metformin was 5.3 so I am not even close to pre dibetic there but my daily blood sugar is alway ~100 for 80% of my day and I have that predawn thing where my BS is 130 when I first wake,
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I have an a1c that is always 5.1 or 5.3 for the past 2 years. I started metformin 500mg 2x daily 1 year ago and nothing seems to have changed.
My morning fasting glucose is always 100-115 when tested at the doctor. My regular doctor says no way do you have diabetes, and Defy tells me my a1c is great but the fasting glucose isn’t ideal. Just yesterday I had an appt with Defy and he briefly mentioned the morning rise but I didn’t ask more about it at the time. Do you know more about this dawn thing?
You can google the dawn effect Basicly the term used to describe an abnormal early-morning increase in blood sugar (glucose) — usually between 2 a.m. and 8 a.m.
We seem to be doing about the same thing and getting the same results. I am planning to stop taking the metformin and see if anything changes.
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Just a little update on my thread. I had heard some say that IM could get levels higher than sub q, my doc also believed that. Never seen any proof though or anyone experience it, but my experience did end up with a interesting result. When I first moved to injections I started with 30mg daily sub and after labs was somewhere over 1300 ng/dl. Doctor wanted me to drop to 25 mg daily. At that time decided I wanted to see if I felt any different with IM and was curious if any truth to different levels between the two methods so moved to daily shallow IM. Just had labs done and I am at 1429 ng/dl. Felt no different between the two methods but even lowering dosage my levels went higher on shallow IM. Thought that was interesting result and thought I would share.
On another note I was able to start 5mg cialis daily to see how that would work for me. Unfortunately I am in that 8% that gets heartburn from it, even at 5mg. Got me some generic pepcid or xantec to see if it would help but only helped a little yesterday. Thinking I might cut the pill in half for a little bit and maybe titrate up if that works, later. Holy shit that was bad heartburn though, bad enough woke me up in the middle of the night and had to munch on some tums.
Only 8% get heartburn? That sucks I am also one of them when taking 5mg. I got some
Omeprazole from Costco that fixed it. At the same time, I stopped the cialis for a few day. I started taking 1/2 tab for a week, then alternating days 1/2 and 3/4 for a week, then 3/4 for a week, then finally 1 full tablet every day. The gradual taper seemed to help. I have no idea if the omprazole or the taper is what changed things for me. I have noticed that carb heavy snacks are what makes the heartburn start for me. If I can avoid junk food carbs then I pretty much rarely have heartburn anymore.
Yeah thats what I have read. Wouldn’t suprise me if more suffer from it. Seems to be better today, started on the xantec and skipped yesterday’s dose. Only took half today so hopefully I can just titrate up later.
What’s up everyone? Haven’t been around much and when I have, I have been quite and just reading from a few guys that I enjoy what they have to say. Social media was starting to take a toll on my mental well being, so have been trying to take a hiatus and when I do drop in just stay quite.
As an update, I am still injecting 18mg daily, taking 75mg of T4 daily and 5-10mg taldafil close to daily, not real consistent on it. Feeling really good there. Because of covid and no gym for a while and drinking a little more than I should I thinked it messed with my levels and total T dropped and estrogen went up. Still felt really good though so not worried about it. Had a good time at my father-in-laws for his birthday the weekend right before last labs so I bet that played a part also. Back in the gym and getting back on track now. Ended up losing around 15 lbs. Not in the most healthy way as 10 of it was from working on my truck 10-12 hrs a day while skipping meals and being in 100°+ temps, lol, but it got the ball rolling so I will take it.
Anyways, hope all are well and healthy.