38, Tired and Frustrated

Daily creams has no esters attached to testosterone, it hits the bloodstream and testosterone and estrogen peaks with 1-2 hours, with injections you can control size of the peaks, a large injection will see large peaks and a small injection sees a smaller peaks, imagine the size of the peak of 100mg versus 10mg per injection.

Massive difference, now imagine how steady of a levels you can have on daily versus weekly, these smaller steadier levels tend to keep estrogen spikes very small, large injections would see my estrogen sky high.

I can inject 100mg and see estrogen several time the ranges, or I can inject daily and see estrogen under 30 pg/mL. You don’t get that type of control on creams.

I’m not saying creams don’t work well, I’m saying if having problems controlling estrogen on creams, injectable T is easier to control all levels.

Creams are more stable and it’s immediate not having to wait 6 weeks or more to build up your levels. It also absorbs directly into the system and does not have to process through the liver like injections. E2 is lower with cream as well. Creams bring levels higher with smaller dosages than injections. Everything I have realized and been told by my prescriber.

That makes sense. I thought creams still had the esters as it is still test cypionate just different delivery method. I’m going to dig into that more as I would like to get off an AI so if that is the case I would prefer that

Maybe but I think cream is more immediate. If you have high e2 issues on injections it can take weeks to lower the levels … with cream you can see the change in a matter of hours or days. .

That is what I was led to believe also. Always thought cream was most ideal but ran the risk of poor absorption.

You only have poor absorption is it’s not compounded well… many folks had issues with bad pharmacies and then realize how good cream is when they get a cream with proper dose. One guy said he would take 10 clicks and it didn’t work. He found a good pharmacy and he felt the difference immediately.

I would suggest you take labs while you have this hbp condition.

CBC - is your blood to thick?
Metabolic panel
Total t
Free t
Estradiol

BTW my blood pressure was high when my testosterone and estrogen was low. It’s possible your estrogen is low on the ai causing this.

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Dont believe my blood is too thick as I just did a double red donation about a month ago and it was within that week after that I read high BP. Never know for sure without labs though. I am planning on getting bloods here soon and getting DHT, free t, total t and e2.

You say you have high blood pressure and headaches. Be cautious and should get CBC ANd metabolic Panel too. Imo
I would even Check TSH.

Btw if you pay for labs I understand you can do many labs. I am a lab addict as there are free 4 me

Can thyroid affect BP also?

Yeah I pay for labs definitely not free for me. Over $700 for my CBC, t and free t, t4 and tsh, and metabolic last year

TSH I think is a general marker. So if that’s way off- you can further investigate that on follow up.

It’s good to take in case something acute is happening??

I mean we can go crazy and check cortisol etc.

Oh Lord. Man what country are you in?

When I tested last summer it was higher but not outrageous. 2.27 or something like that

I’m in the US

If they were free for me I would be getting anything and everything checked that I could think of but unfortunately that isnt the case.

There a quest one. But check this out.

Let me find the others

This one may be good. Directly with quest

https://questdirect.questdiagnostics.com/

$149 CBC, metabolic panel, cholesterol and urine - there are other packages.too. that’s just an example

Discounted labs is who I am getting my next ones through. Just have to drive 45 min to get them done. When I paid that $700 it was through my family doc and “insurance”.

Check the quest link I added above. Priced Right there in there site.

BTW check around internet. Discount labs has discount codes… Good luck man

Also check this
https://www.peaktestosterone.com/Testosterone_Labs.aspx

I wouldn’t test it then.

Same here, low testosterone affects the cardiovascular system negatively and when testosterone is low, vens narrow and the pituitary sense poor blood flow and therefore increases heart rate to compensate.

I am going to throw in a couple of things. My TSH shot up to 4.0 when I started TRT. I went off to try a restart because I think that I may be secondary and not primary and my TSH dropped right back down. I would not get real worked up about thyroid numbers initially, give them some time to adjust.
I did have some success with Arginine lowering my blood pressure. Not super consistently, but it did have a definite effect. But, I am also learning about my gene mutations and trying to understand how they might effect all of that.