Updated Lab results attached and I am a bit surprised. My Estradiol came back at 11.00 pg/mL (REF RANGE 7.6-42.6), down from 23.0 pg/mL (REF RANGE 11-44). The attached blood work was at the .5 mg anastrozole per week and prior to my last post where I started to increase anastrozole dosing. As mentioned in my last post, I was holding a lot of water weight and had ballooned from 226 lb pre-TRT to 236 lb as of Monday morning. After my blood work Monday I performed my injection in conjunction with .5 mg anastrozole and another .25 mg anastrozole on Wednesday with my second injection. Today, Thursday, I weighed in at 225 lb and am holding a lot less water as evidenced by the mirror. I do not feel any of the symptoms of low Estrogen such as achy bones.
I wonder if the swing is due to the different reference ranges for each test, different labs, interaction with the anastrozole and the testing method, or some other reason. It looks like I am an over responder but I am hesitant to bring my anastrozole dosage back down to .5 mg as I would hate to put all that water weight back on. Is low estrogen known to cause water weight gain? Any insight prior to meeting with my doctor on Saturday is appreciated.

