22 Testosterone 260, TSH 5.33 in a Crash-Like State

Oh I see!, you guys over the pond are so lucky. I have no clue what to do then, I was thinking of swapping needles on the same syringe, until the ampoule’s worth is finished… but the syringe is just sitting there, so not sure if that is safe.

My doctor loaded two syringes from the sustanon 250 and capped with a needle and said I could keep it for next week’s dose—I don’t know how good practice this is.

The worst is that there is a shortage of hCG in the UK atm, and I maybe only able to get 5000IU so splitting that ampoule into 250s will be problematic!

Confused? :slightly_frowning_face:

We are very lucky over here and there are those here who are trying to make it easier on the folks over there, change is coming. Already there are websites where you can order your own SHBG testing, soon I hope every other test as well. Hopefully by then TRT won’t be so taboo and become more accepted. I didn’t comment on the syringes because I simply don’t want to give the wrong advice, I do know that after awhile the rubber plunger becomes weakened when exposed to the test solution. How long it takes to get to that point is unknown to me.

@systemlord, @KSman

So… coming back to this thread to update. I don’t know if people will see it? how old thread updates work.

I am currently in a pickle as my anxiety has sky-rocketed, I suspect my estrogen needs to be controlled. I have ordered a generic anastrazole 30 x 1mg, and I will get my test results from last week soon.

I feel a bit trapped, and desperate as can’t concentrate on anything. I have had anxiety ever since finasteride, and was doing better until the last 2 weeks.

I have a question about the AI. As I am so anxious, it is difficult to sort it out, and the mixing seems complicated. Can I not use a 5ml syringe, squirt 5ml in a sterile vile with 5mg of tablets. Then shake thoroughly, and then put in the fridge? Rather than buy a gradated cylinder or something.

Secondly to extract the dosage, do I need a graduated pipette? Can I not keep one 1ml insulin syringe and just use that to take the dose from the sterile vial in the fridge, and measure say 0.25ml for 0.25mg and squirt that into a glass and drink ?

If this is not possible I would appreciate, a pointer on amazon uk of the minimum equipment I need, that is cheap, so I have it ready, given that I have 5ml syringe and sterile vial.

My estrogen was very low before starting on TRT, so I think it took time to get up on TRT, I had a phase where I was feeling great, but it has crept up on me. I don’t get morning erections, have extreme anxiety.

My current protocol:

—175mg of sustanon per week (125mg E5D)
—250 IU EOD of hcg
—thyroid grains—I am dosing up and am currently at 2 grains.

I increased my T dose in January, up from 125mg E7D, and initially felt the best I have in years. My leg hair and arm hair has grown back a bit (I don’t think I had the testosterone to sustain this), some beard follicles have grown(never grew since finasteride when I was 20), I no longer have joint pain and loads of other little symptoms, (weird and extreme testicle pain, that was way worse after ejaculation or trying to working out), non-existent sexual function etc.

It was incredible, I realise how the last three years I have been just anxious and barely alive, with no memory etc. or capacity to concentrate on anything as I am so high strung. I used to love reading, but could never concentrate, as my mind would wonder to some stress, and there would be rapid proliferation of thoughts. I managed to string 2 weeks of actually starting to get some things done. But then last week I started feeling really anxious and was rushing about having loads of pointless appointments about varicocele and trying to get blood tests.

My thyroid function deserted me, after I had this crash— I was literally freezing, I had to wear 5 ski jackets some times. Body temperature came back as 35 C, and sometimes lower, every time I measured it. I had my TSH retested and it came at 4.2. Then I had a test before I went on thyroid 3 weeks ago and my T4 came well below the range. I have warmed up since starting the grains so think that has definitely worked and I do not think is related to the anxiety.

I have quite a lot of vestigial damage from having my hormones poor for so long (3 years) and having such extreme anxiety for that long. I have finally got a varicocele embolization in the pipe line on the NHS. The pain is more an annoyance, but I have read that fixing that may effect my hormonal production.

Sorry for the long post, any thoughts on protocol and most importantly help with the AI would be great. I will post my results from last week soon, but it feels like oestrogen has shot up more this week as well.

Blood pressure is also high, but I am hoping after controlling estrogen it will come down, it has always been a bit high since the finasteride saga and constant anxiety. I have booked in blood donations as well, as I don’t see how this can hurt and may help with HCT etc.

as the help here before got me able to use the hcg and testosterone correctly, which makes the protocol so much better, ie using the correct needle sizes, SQ. dosing schedule, hcg amount.

right results, hormones a bit all over the place.

At the trough end of five days.
estrogen 39.3 pg/mL
Testosterone 905

Oestradiol 144 pmol/L
Testosterone 31.1 nmol/L

TSH 0.09 mu/L
Free T4 8.6 pmol/L
Free T3 7 pmol/L

Red blood cell (RBC) count 5.27 10*12/L 4.5 - 6.5
Haemoglobin estimation 166 g/L 130 - 170
Haematocrit 0.468 0.4 - 0.5
Haemoglobin estimation 166 g/L (130 - 170)
Mean corpusclar haemoglobin 31.5 pg 27 - 32

So… I think I am dosing too high right, and should move back down to at least E6 days.

Or is it the estrogen causing my anxiety problems etc.?

Should I still go on an AI with an estrogen of 40, I think it was on an upward trajectory as it was starting from a deficit of 15?

What dosage should I start out with the AI, I am thinking splitting the 1mg pill roughly into 3 and taking EOD so total of 1.15 mg a week. would this be right?

How quickly does the AI take to work, as am feeling pretty scatty.

My thyroid I am slowly going to go up in the grains, so the T4 should come up, and I have been doing a lot better since it has been suppressed.

With the testosterone and oestrogen, what dosage schedule would get me to about 900 T and 22 Estrogen, considering at my trough on 175mg (and benefits from more regular dosing, E5D) I had above 900 Testosterone?

I’m thinking 0.25mg EOD Anastrazole, and going back to E7D(125mg, one injection) and retest in 4-5 weeks? Or would E6D or E6.5D seem better.

As I am feeling rough now, I am thinking of missing my hCG dose for a day and waiting 8 days until my next injection and do anastrazoe 0.33mg EOD for a pill, to hopefully get estrogen down. Or is this not necessary.

I’m thinking of buying https://www.amazon.co.uk/Amber-Glass-Bottles-Dropper-Pipettes/dp/B00BDTN0K4/ref=sr_1_17?ie=UTF8&qid=1519246155&sr=8-17&keywords=Glass+Bottle+with+Dropper+Pipette, and mixing 5mg with 5ml vodka, and using the same insulin syringe to measure out 0.25ml into glass and drink. Is this flawed because the 31g is too small ?

I do feel uncomfortable and this has prompted me to have blood tests every 4 weeks for the next 12 weeks. How long should I wait until my next dosage? To try and normalise my levels, as after the blood test I think I would have been adding fuel to the fire, and shudder to think what my levels were this week. I am thinking of waiting 12 days until my next injection.

With E2=42pg/ml and goal of 22
Increase dose by a factor of 42/22

fT3 should be midrange or a bit higher.

Estrogen is definitely an issue, I really couldn’t function with it above 40.

My new results:

Testosterone: 628
Oestradiol: 25
TSH: 0.152
Free T4: 9.13(7.87-14.45)
Free T3: 4.99 (3.95-6.16)

This was after a protocol of
—125mg/week days Sustanon split into two divided doses
—250IU EOD hCG
—1 mg/week Anastrazole taken in three divided doses
—2.5 grains of NDT

This is the first time I have had my hormones in the ranges so boy does it feel good. It really has given me my life back. I have felt a bit lack of motivation/ and still no sexual function, I am 23, so maybe higher T would be slightly better. Although these problems could be due to propranolol (40mg a day) which I started taking while my estrogen was very high to try and cope.

I am going to amend my protocol
to
—145mg/week Sustanon (E3 day dosing schedule—I feel I could just do the full 125mg every 6 days?)
—1.25mg/week Anastrazole taken in 4 divided doses(I don’t know how important it is to divide the doses, rather than taking 0.6 twice a week
—250IU EOD hCG
—3 grains of NDT(2 in am, 1 in pm)

So much better, it has taken me 4 months to realise blood tests are important and to get everything at the right level. Which is nothing compared to the 3 years of struggle before, after I took finasteride. This is the first time my anxiety has abated considerably, I was currently taking time off, and living as a hermit, I had already taken a year out previously, so have had two years out of society. Now I want to get back in, and start living again!!

On paper it doesn’t look too bad, as people in the UK usually have a gap year. So it is one more year. I am lucky that I stumbled upon the answer, rather than continuing the three year downward spiral. I felt like an 80 year old man, before, new health conditions cropping up, memory and brain power reduced, fear with everything. Socially withdrawn.

Now a lot of things have come back, I realise how powerful young men are, in thought, sport and ability to be creative mentally.

Now I have to figure out what to do with my life and try and reintegrate back into society slowly, as I do have a lot of baggage from the experience, and anxiety will probably be a problem for a while.

I am going to still have regular blood tests until I am completely happy and have had two consecutive ones that are pretty similar on same dose.