You rarely see anyone doing weighted stair climbs anymore. The main reason is because they're so damned hard. I used these when training for the Fire Fighter Combat Challenge (the hardest two minutes in sports) but they're great for all-around metabolic conditioning.
It's very simple. Grab a set of dumbbells and walk up the stairs as fast as you can. When you get to the top, walk back down. Rest as needed and go again. Repeat until your heart explodes out of your chest, your lungs collapse, or your legs give out. Whatever comes first.
It's simple, yes, but easy? Don't kid yourself. After 5-10 minutes you'll be done.
If you want to correct a few muscle imbalances you may have created before you knew better, or if you want to fortify the integrity of your shoulder joints and maybe even improve your posture, then this might be just the article you need.
What happens when a bodybuilder and a nutrition store owner get together and make a baby? What happens when this baby is raised on health foods? What happens when she starts training with weights at age 14?